DNA Cytosine Demethylation: Are We Getting Close?

DNA Cytosine Demethylation: Are We Getting Close?

Whether 5-methylcytosine (meC) can be enzymatically removed from vertebrate DNA has been the subject of extensive study and also some controversy. Rai et al. (2008) now report that cytosine demethylation can be accomplished in a one-cell zebrafish embryo by the combined action of a cytidine deaminase and a thymine DNA glycosylase.

Automated Debugging: Are We Close

2 Computer Automated Debugging: Are We Close? F or the past 50 years, software engineers have enjoyed tremendous productivity increases as more and more tasks have become automated. Unfortunately, debugging—the process of identifying and correcting a fail-ure's root cause—seems to be the exception, remaining as labor-intensive and painful as it was five decades ago. An engineer or programmer st...

Solving the Mystery of Dengue in Iran; Are We Close to an Answer?

Dengue fever is a mosquito-borne infection which is endemic in Southeast Asia. Although it has not been distributed in Iran, locating near other countries where the Dengue has been revealed is a threat for Iran because different connection between countries may increase the rate of infection.

Myeloid leukemia: are we getting better?☆

short time. There is a need to provide a post remission therhe study by Callera et al., published in this issue of the evista Brasileira de Hematologia e Hemoterapia (RBHH),1 eveals evidence of a continuous decrease in the mortality ate in adult patients with myeloid leukemias from 1994 to 011 in southeast Brazil. Undoubtedly, this decline is related o the better understanding and treatment of ...

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